Clinical Biology (China)
This study is a collaboration between RECOVER WP5, Pasteur Institute (IP) of Shanghai, and the Chinese Academy of Science Affiliated Hospital in Hefei. IP Shanghai provides the laboratory research support for the Chinese Academy of Science Affiliated Hospital in Hefei, which is a designated centre for the case of patients infected with SARS-CoV-2.
The research objectives of the patient-based laboratory studies are:
- Describe the natural history of SARS-CoV-2 in relation to transmissibility in patients admitted to the Hefei hospital;
- Provide characterisation of viruses, to allow phenotypic characterisation, and characterisation of immune response for rapid risk assessment purpose;
- Assess the possible role of prior coronavirus exposures to susceptibility, severity, and transmissibility.
The following population-based study objectives will be addressed:
- Monitor evolution of the epidemic and contribute to the reference database for precision public health by characterization of viral genomes and phenotypic traits.